Jelang tutup tahun 2021, Badan Kesehatan Dunia (World Health Organization/WHO) mengeluarkan peringatkan bahwa dua varian SARS-CoV-2 yakni Omicron dan Delta yang kini tengah beredar, bisa menimbulkan "tsunami COVID-19". Kondisi ini juga diprediksi akan memberi tekanan besar pada sistem kesehatan nasional.
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